The Effect of Lutein, Zeaxanthin, and Meso-Zeaxanthin Supplementation on Visual Performance: A Systematic Review

Abstract

Objective: To determine whether nutritional supplementation with lutein (L), zeaxanthin (Z), and/or mesozeaxanthin (MZ) results in improved human visual performance. Method: A systematic literature search was performed on the effects of L, Z, and/or MZ supplementation on human visual performance. The databases which were queried were Pubmed and ScienceDirect. Results: A totalof 19 studies were identified and analyzed. Combined analysis of all these studies revealed that 1) there were no safety concerns from L, Z, and MZ supplementation, and 2) with supplementation there was either improvement of visual performance or there was no change in visual performance. There were no studies in which visual performance decreased with supplementation. Several promising trends materialized from these studies: contrast sensitivity, glare disability, photostress recovery, critical flicker fusion frequency, and photophobia all showed general improvement with supplementation. Visual acuity and color vision, on the other hand, showed no improvement, or had inconclusive results.

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Document Details

Document Type
Technical Report
Publication Date
Jun 27, 2019
Accession Number
AD1083475

Entities

People

  • Aaron Mcatee
  • James Q. Truong
  • Judith A. Driscoll
  • Kevin J. Obrien
  • Leonard A. Temme
  • Paul M. Onge
  • Raquel M. Goosey-gerdes

Organizations

  • United States Army Aeromedical Research Lab

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Antioxidants
  • Color Vision
  • Computers
  • Diseases And Disorders
  • Eye Diseases
  • Frequency
  • Literature Surveys
  • Ophthalmology
  • Pilot Studies
  • Quality Of Life
  • Retinal Diseases
  • Rotary Wing Aircraft
  • Sensitivity
  • Statistical Analysis
  • United States
  • Visual Acuity
  • Visual Perception

Fields of Study

  • Medicine

Readers

  • Information Retrieval
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Vision Science/Vision Psychology/Cognitive Neuroscience.