Environmental Fate of Ketamine in Soil and Relevant Waters
Abstract
In this study, our objective was to assess the stability and persistence of ketamine in four soil types and seven different water sources. We wanted to determine the distribution of ketamine when it is in contact with soil and water. Soil samples in contact with waters from a variety of sources were spiked with a known amount of ketamine solution and were then extracted after several contact time points to track compound recovery and distribution. The water samples were also spiked with known amounts of ketamine, and aliquots were taken at different time points for analysis. The results showed that the amount of ketamine in contact with the soils was nearly constant for up to 12 weeks and accounted for 6080 of the amount of the spike. Ketamine was also present in the aqueous phase, which enabled calculation of the soil-partitioning distribution coefficient, Kd. The water samples were stable up to 13 weeks. These results indicate that ketamine is relatively stable in water and moist soils. The resulting data also indicate that ketamine is mobile in the environment.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 07, 2019
- Accession Number
- AD1083999
Entities
People
- Bruce E. King
- Kenneth B. Sumpter
- Morgan Minyard
- Roberta Xega