Latex Content in Adult Vaccines

Abstract

Hypersensitivity reactions to natural rubber latex are well-characterized occupational concerns for health care personnel. The prevalence of latex allergy among health care providers is reported to be as high as 9.7%. The symptoms range from mild local cutaneous reactions to generalized urticaria, angioedema, allergic rhinitis, respiratory symptoms, and even life-threating or fatal anaphylaxis. Health care providers are also at increased risk for exposure and possibly transmission of vaccine preventable diseases. Therefore, many healthcare facilities require providers to be vaccinated against these diseases to maintain employment. Specifically, hepatitis B and Tdap vaccinations are recommended by the Center for Disease Control for healthcare workers. Many of these vaccines come in single dose prefilled syringes whose packaged inserts have warning that state, "the tip caps of the prefilled syringes contain natural rubber latex which may cause allergic reactions." The Advisory Committee on Immunization Practices and the Adverse reaction to vaccine practice parameter 2012 update, recommends that if a person has a history of a severe anaphylactic reaction to latex, then vaccines supplied in vials or syringes should be avoided.

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Document Details

Document Type
Technical Report
Publication Date
Sep 13, 2019
Accession Number
AD1084936

Entities

People

  • Derek M. Smith
  • Julie A. Davenport
  • Robert Gomez

Organizations

  • 59th Medical Wing

Tags

DTIC Thesaurus Topics

  • Allergy And Immunology
  • Anaphylaxis
  • Department Of Defense
  • Diseases And Disorders
  • Health
  • Health Care
  • Health Care Facilities
  • Health Services
  • Hypersensitivity
  • Medical Personnel
  • Natural Rubber
  • Therapy

Fields of Study

  • Medicine

Readers

  • Immunology
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Toxicology/Environmental Toxicology

Technology Areas

  • Biotechnology