Treatment of Early Post-op Wound Infection after Internal Fixation

Abstract

Postoperative infection is one of the most prevalent and challenging complications faced by orthopaedic surgeons and patients in both the military and civilian populations. The wounds are contaminated or colonized at the time of injury, during the course of therapy, or both. Infection is always a possibility with any surgical intervention, particularly in the setting of trauma where multiple factors make the prevention and treatment of these infections very complicated. As of October 1, 2018, a total of 2058 patients have been screened for eligibility, and of these, 920 were eligible. Of the 920 eligible patients, 232 (25% of eligible) were consented and enrolled into the RCT; 130 (14% of eligible) were consented and enrolled into the observational arm. As of October 1, 2019, the study has been closed for enrollment and we reached 87.9% of our total enrollment. Two hundred and ninety two patients have completed the study.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2019
Accession Number
AD1085949

Entities

People

  • William Obremskey

Organizations

  • Vanderbilt University

Tags

DTIC Thesaurus Topics

  • Anti-Infective Agents
  • Biomedical Research
  • Department Of Defense
  • Infection
  • Information Operations
  • Maryland
  • Orthopedic Surgical Procedures
  • Universities
  • Wound Infections
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Microbial Pathology
  • Neurotrauma and Rehabilitation Medicine.
  • Psychological Intervention/Treatment for Stress, Anxiety, PTSD, and Related Emotional and Cognitive Health Symptoms.