Bio-inspired Assembly at Two Length Scales: Bridging Intermolecular Peptide Self-Assembly and Particle Phase Behavior in Two-Dimensions
Abstract
The over arching goal of this grant was to couple the molecular and colloidal length scales by co-assembling periodically sequenced polypeptides and anisotropic Janus particles at interfaces. The work was divided into four tasks First, we synthesized several high molecular weight polypeptides with an alternating periodicity resulting in amphiphilic -strands when confined to interfaces. A total of 14 dipeptides were synthesized, and four were successfully polymerized. Second, we synthesized several anisotropic Janus particles, varying the properties of the Janus particles along two distinct axes, (1) the size of the particles and (2) the degree of anisotropy. Third, we used a Langmuir trough duplexed with a micro-Brewster angle microscope to image the interfacial assembly and the phase behavior of the polypeptides and the particles under confinement. Fourth, we examined both the single-component and two-component phase behavior of the periodically sequenced polypeptides and the Janus particles confined at an air-water interface.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 17, 2019
- Accession Number
- AD1085979
Entities
People
- Raymond S. Tu
Organizations
- City College of New York