A Multidisciplinary Approach to Study the Role of the Gut Microbiome in Relapsing and Progressive MS

Abstract

We hypothesize that specific human GI microbiota can alter the balance of inflammatory and regulatory immune cell populations thus leading to disease in genetically susceptible hosts. Furthermore, we hypothesize that gut microbiota from subjects with RMS and PPMS is fundamentally different and can elicit distinguishable effects when transferred into susceptible animal models of the disease.

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Document Details

Document Type
Technical Report
Publication Date
Oct 29, 2018
Accession Number
AD1087032

Entities

People

  • Sergio E Baranzini

Organizations

  • University of California

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • California
  • Contracts
  • Data Integration
  • Department Of Defense
  • Diseases And Disorders
  • Dna Sequence Analysis
  • Gut Microbiome
  • Information Operations
  • Law
  • Maryland
  • Microbiomes
  • Multiple Sclerosis
  • New York
  • Patent Applications
  • Professional Development
  • Technology Transfer

Fields of Study

  • Biology

Readers

  • Medical Imaging.
  • Microbial Pathology
  • Oncology

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech