Microtox Testing of Thirteen Replacement Candidates for Methylenedianiline, August-September 2018

Abstract

The toxicological properties of 13 replacement candidates for 4, 4-methylenedianiline (MDA) are under assessment. MDA is a compound used in the preparation of a polymer resin, PMR-15, which is used in the fabrication of high temperature-resistant parts for rockets and similar applications. MDA is mutagenic and is a high priority for replacement with non-mutagenic substitutes. The aquatic toxicity of these 13 candidates was predicted using the Microtox Acute Toxicity Test System, a bioluminescent bacterial aquatic toxicity test. Data from this study are used to assist in making environmental and health-based decisions regarding the design and selection of formulas and materials for future development of new munition compounds.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2019
Accession Number
AD1087254

Entities

People

  • Emily N. Reinke

Organizations

  • United States Army Center for Health Promotion and Preventive Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Data Analysis
  • Department Of Defense
  • Environment
  • Environmental Protection
  • Experimental Design
  • Fish
  • Health
  • High Temperature
  • Life Cycles
  • Materials Laboratories
  • Military Research
  • New York
  • Occupational Safety And Health
  • Preventive Medicine
  • Public Health
  • Range Finding
  • Regulations
  • Risk
  • Risk Analysis
  • Risk Management
  • Solubility
  • Standards
  • Technology Assessment
  • Toxicity
  • Toxicology
  • United Nations
  • United States
  • Zinc Compounds

Readers

  • Instructional Design and Training Evaluation.
  • Reinforced Composite Materials
  • Toxicology/Environmental Toxicology