Treatment of Spinal Cord Ischemia with Cell Impermeant-Based Resuscitation

Abstract

In the first year we determined the optimal polymer sizes required to produce a theoretical optimized osmotic transfer of metabolic water out of the spinal cord tissues after injury and into the capillary space for rapid removal by convective transfer. In this years studies, we have optimized the spinal cord injury models and the polytrauma models that will be used to test the effectiveness of osmotic PEG polymer treatment.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2019
Accession Number
AD1088461

Entities

People

  • Martin J Mangino

Organizations

  • Virginia Commonwealth University

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Biological Staining And Labeling
  • Biomedical Research
  • Blood
  • Blood Flow
  • Boundaries
  • Cardiovascular Physiological Processes
  • Cells
  • Coefficients
  • General Surgery
  • Health Services
  • Hemorrhagic Shock
  • Ischemia
  • Medical Personnel
  • Microvessels
  • Molecules
  • Polymers
  • Recovery
  • Reflection
  • Resuscitation
  • Spinal Cord
  • Spinal Injuries
  • Spine
  • Students
  • Surgery
  • Therapy

Readers

  • Atmospheric Science / Meteorology, specifically Wind Wave Turbulence.
  • Neurotrauma and Rehabilitation Medicine.
  • Polymer Science and Technology

Technology Areas

  • Space