Interactions of Closed Loop Control PEEP oxygenation and Fluid Therapy

Abstract

Background: Closed loop control mechanical ventilation has been reported to potentially reduce ventilator weaning time, burden on medical caregivers, and improve comfort during mechanical ventilation. However, the influence of closed loop control PEEP adjustment, on fluid requirements in the acute phase and cardiopulmonary dysfunction, remains unknown. The aim of this study was to investigate the impact of closed loop ventilation and PEEP/FiO2 on decision support-based fluid resuscitation and respiratory mechanics/gas exchange using a clinically relevant ovine model of burn and smoke inhalation.

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Document Details

Document Type
Technical Report
Publication Date
Sep 30, 2019
Accession Number
AD1089126

Entities

People

  • Michael Kinskey

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Airway Management
  • Analgesia
  • Anesthesia
  • Arteries
  • Blood
  • Cardiovascular Physiological Phenomena
  • Drug Therapy
  • Health Services
  • Laboratory Animals
  • Oxygenation
  • Respiratory Physiological Phenomena
  • Therapy
  • Veins
  • Wounds And Injuries

Readers

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  • Trauma Surgery or Emergency Medicine.