Development of a Supercooled Limb Preservation Protocol

Abstract

The project aims to develop a novel technology to preserve vascular composite allografts for extended periods. This project uses a rat limb transplant model and aims to preserve grafts for up to 3 days. In the second year, we developed a supercooled VCA preservation modality and tested by tissue energy charge. We are finishing testing the duration limits of this protocol. Year 3 will focus on transplant testing of the protocol.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2019
Accession Number
AD1089832

Entities

People

  • Korkut Uygun

Organizations

  • Massachusetts General Hospital

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Allografts
  • Blood Vessels
  • Cold Storage
  • Composite Materials
  • Department Of Defense
  • Experimental Design
  • Health Services
  • Management Personnel
  • Materials
  • Medical Personnel
  • Patent Applications
  • Professional Development
  • Students
  • Surgery
  • Systems Engineering
  • Transplants

Fields of Study

  • Biology
  • Physics

Readers

  • Systems Analysis and Design
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology