Multispecies, Integrative GWAS for Focal Segmental Glomerulosclerosis

Abstract

The overall goals of this project are to identify novel susceptibility variants to human nephrotic syndrome caused by focal segmental glomerulosclerosis (FSGS) and minimal change disease (MCD). Using a variety of statistical and genetic approaches, including genome wide association analysis and rare copy number variations (CNVs) mapping. Data are then integrated with genetic analyses from mouse models from the partnering project. The identification of novel variants will provide insight into some of the genetic mechanisms that underlie FSGS.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2019
Accession Number
AD1092013

Entities

People

  • Simone Sanna-cherchi

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Caucasians
  • Data Analysis
  • Diseases And Disorders
  • Ethnic Groups
  • Genes
  • Genetic Phenomena
  • Genetics
  • Genome
  • Identification
  • Kidney Diseases
  • Medical Genetics
  • Medical Personnel
  • New York
  • Professional Development
  • Students
  • Training

Fields of Study

  • Biology

Readers

  • Molecular and Cellular Biology
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology