Rapid and Sensitive THz Bio-Sensing

Abstract

This is the final report on the progress achieved under ARO grant to develop a novel, compact Terahertz (THz) spectroscopy system with and without moving parts for realtime, in-situ, rapid, and sensitive bio and condensed matter sensing. The proposed THz unit would increase the speed of measurements and improve analysis times to obtain THz spectra of biological and chemical agents as well as analysis of the absorption and refraction indices of those agents. We focused on investigating the actual THz-spectrometer with and without a grating time delay unit. The grating, by its nature, creates a natural time delay. We included a grating in a real THz device and investigated the parameters of THz pulse time delayed by the grating. After that, with the grating included in the real THz device we investigated THz spectra of real biological agents i.e. Alzheimer-Disease (AD) brain tissue and the Breast Cancer Cells (BCC). A paper was published on AD and Normal Brain and breast cells .

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Document Details

Document Type
Technical Report
Publication Date
Jan 28, 2020
Accession Number
AD1092881

Entities

People

  • Aleksandra Alimova
  • Robert Alfano
  • Wubao Wang
  • Xiaohui Ni

Organizations

  • Research Foundation of The City University of New York

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Absorption
  • Absorption Spectra
  • Alzheimer Disease
  • Chemical Warfare Agents
  • Detection
  • Detectors
  • Diseases And Disorders
  • Geometric Forms
  • Kerr Effects
  • Near Infrared Radiation
  • Optical Detection
  • Optics
  • Radiation
  • Refraction
  • Refractive Index
  • Spectra
  • Spectroscopy

Readers

  • Nanofabrication and Microfabrication.
  • Nanoscale Plasmonic Nanotechnology
  • Radar Systems Engineering.