Multimodality Imaging Platform for Neurovascular Bundle Sparing Prostate Radiotherapy to Preserve Sexual Function

Abstract

The overall project goal is to develop an advanced imaging technology to assess treatment-related erectile dysfunction and thereby improve sexual outcomes and quality of life of prostate-cancer survivors. This project has 3 major steps: (1) develop a new technique for combining MRI and ultrasound images in a way that can allow physicians to see the neurovascular bundle (NVB) clearly and reliably, (2) confirm that these new imaging findings match the patients outcome with respect to their erectile function, and (3) use the new imaging techniques to reduce radiation dose to the NVB. Over the current period, we have made significant progress in the development of the technology to combine MRI and Ultrasound images (including Doppler images), and made significant progress on subject accrual for the calibration study and longitudinal clinical study that is the core of the project.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2019
Accession Number
AD1093866

Entities

People

  • Ashesh B. Jani

Organizations

  • Emory University

Tags

Communities of Interest

  • Air Platforms
  • Autonomy
  • C4I
  • Human Systems

DTIC Thesaurus Topics

  • Accuracy
  • Artificial Intelligence Software
  • Deep Learning
  • Diagnostic Imaging
  • Dimensionality Reduction
  • High Resolution
  • Image Processing
  • Image Segmentation
  • Imaging Techniques
  • Machine Learning
  • Magnetic Resonance
  • Medical Personnel
  • Neural Networks
  • Radiation Oncology
  • Supervised Machine Learning
  • Three Dimensional
  • Two Dimensional

Fields of Study

  • Medicine
  • Physics

Readers

  • Clinical Trial Research.
  • Oncology
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.