The Comparative Efficacy of the Masquelet Versus Titanium Mesh Cage Reconstruction Techniques for the Treatment of Large Long Bone Deficiencies
Abstract
The study comprises a single center, randomized, two-arm clinical trial conducted at the Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch at Galveston, Texas, with a primary objective to assess and compare the functional outcomes of patients with large segmental bone defects reconstructed with the Masquelet technique (MT) versus the titanium mesh cage technique (TMCT) in combination with bone grating. The secondary objectives include the radiographic determination of defect healing, and comparative assessment of cost and resource expenditures between the two techniques. From 25 patients with segmental defects presented to our institution throughout the entire trial period, 16 met the study eligibility criteria and were successfully enrolled, and they include 9 MT, 7 TMCT. Within the last 12-month study period encompassing this report, 2 patients completed the study (1 MT and 1 TMCT), and 7 patients are still participating. These 7 study participating subjects (4 MT, 3 TMCT) are being followed, and their study courses are uneventful. There was 1 potentially eligible study patient identified, however, ultimately, he was concluded not meeting the study inclusion criteria. The trial is ongoing and patient enrollment is still in progress.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2018
- Accession Number
- AD1094166
Entities
People
- Ronald W. Lindsey
- Zbigniew Gugala
Organizations
- University of Texas Medical Branch