Development of a Surface-Enhanced Raman Spectroscopy (SERS)-Based Microfluidic Device for Narcotics Detection

Abstract

A microfluidic device is being developed by University of California, Santa Barbara as part of a joint effort with the U.S. Army to provide a portable, rapid drug-detection device for drugs and explosives. Surface-enhanced Raman spectroscopy (SERS) was used to provide a sensitive, selective detection technique within the microfluidic platform that employs metallic nanoparticles as the SERS medium. Issues with the devices performance, including reproducibility of flows and targeted binding of analytes, were identified as limitations of the technology. This report details the attempts to remedy these issues and make the technology field-deployable.

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Document Details

Document Type
Technical Report
Publication Date
Mar 31, 2020
Accession Number
AD1094415

Entities

People

  • Ashish Tripathi
  • Augustus Iii W. Fountain
  • Erik Emmons
  • Jason A Guicheteau
  • Neal D. Kline

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical

DTIC Thesaurus Topics

  • Chemical Analysis
  • Chemical Synthesis
  • Chemistry
  • Detection
  • Drug Abuse
  • Explosives
  • Fluid Flow
  • Liquid Chromatography
  • Mass Spectrometry
  • Materials
  • Materials Laboratories
  • Materials Science
  • Metallic Nanoparticles
  • Nanoparticles
  • Raman Spectroscopy
  • Spectra
  • Spectroscopy

Readers

  • Nanoscale Plasmonic Nanotechnology

Technology Areas

  • Biotechnology