Detection of Early Lung Cancer among Military Personnel (DECAMP)

Abstract

The purpose of this work is to develop and validate molecular biomarkers found in blood, tissues, or other bodily fluids, which may be used for the early detection of lung cancer among military personnel and veterans. Over the course of the last year of this award, we have made significant progress towards enrollment in both clinical trials. We have recruited tilde92 percent of the 500 total subjects in the indeterminate pulmonary nodule study (Protocol 1), and tilde69 percent of the 800 total subjects in the longitudinal screening study (Protocol 2). The Leadership, Steering, Adjudication, Biostatistics, Imaging and Biomarker Committees continue to meet regularly. Most notably, significant progress has been made in collection and profiling of biospecimens from both cohorts, which will facilitate the validation of our cancer biomarkers. We have secured additional funding for the DECAMP consortium through July 2022, to ensure the completion of our enrollment goals and study aims. Lastly, we are finalizing discussions regarding dissemination and sharing of DECAMP data in the coming years.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2019
Accession Number
AD1094571

Entities

People

  • Avrum E. Spira
  • Ehab Billatos
  • Elizabeth Moses

Organizations

  • Boston University

Tags

DTIC Thesaurus Topics

  • Biorepositories
  • Biospecimens
  • Biostatistics
  • Blood
  • Cancer
  • Clinical Trials
  • Detection
  • Diseases And Disorders
  • Gene Expression
  • Health Care
  • Health Services
  • Lung Cancer
  • Lung Diseases
  • Medical Personnel
  • Military Medicine
  • Military Personnel
  • Proteins

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