The Effect of Hypobaria on Muscle Inflammation and Regeneration After Injury and Hemorrhagic Shock

Abstract

The purpose of this research is to understand the effect of long-distance flying on recovery after muscle injury and significant bleeding. This situation may affect recovery following combat injuries, especially if wounded service members are traveling from Asia to the United States. The hypothesis, there will be no difference in well-being and white blood cells populations in skeletal muscle between male mice exposed to hypobaria for 16 hours and male mice exposed to normobaria, was supported. In addition, several procedures involved in comparing the effects of two types of resuscitative fluids on muscle recovery and widespread inflammation after significant bleeding were completed. We began procedures to test the hypothesis that long-distance flying at 24 hours after muscle injury and significant bleeding will lead to slower muscle recovery.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2019
Accession Number
AD1094615

Entities

People

  • Barbara St. Pierre Schneider

Organizations

  • University of Nevada, Las Vegas

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Cells
  • Cells
  • Data Analysis
  • Employment
  • Granulocytes
  • Health Services
  • Hemorrhagic Shock
  • Leukocytes
  • Medical Personnel
  • Muscles
  • Peptide Growth Factors
  • Skeletal Muscle
  • Statistical Analysis
  • Students
  • Tissues

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Trauma Surgery or Emergency Medicine.
  • Trauma or Military Medicine