Employing Tissue Oxygen Delivery Calculations to Predict Aeromedical Evacuation Patient Outcomes---A Pilot Study

Abstract

In late 2006/early 2007, the notion of tissue oxygen delivery (DO2) was introduced into the aeromedical evacuation (AE) arena. This so-called DO2 paradigm offered up a coherent approach for Theater Validating Flight Surgeons (TVFS) prescribing supplemental oxygen, transfusions, and cabin altitude restriction (CAR). Research into CAR suggested superior post flight outcomes, which, in turn, suggested that good DO2 (> 7.3 ml O2/kg/min) might be a contributing factor. Using data obtained from a retrospective case-control study where a random sample of 50 CAR patients were matched with 50 Non-CAR patients, the DO2-GUI calculated DO2. Independent variables were DO2 and CAR status with postflight procedures, the dependent variable. While the case-control study demonstrated that CAR was associated with significantly fewer postflight procedures, this pilot study likewise found that good DO2 was associated with significantly fewer postflight procedures (p = 0.002). Additionally, DO2 and the number of postflight procedures exhibited a significant dose-response, inverse relationship (p = 0.045). As DO2 rose, the number of postflight procedures fell.

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Document Details

Document Type
Technical Report
Publication Date
Jan 08, 2020
Accession Number
AD1094791

Entities

People

  • Anthony Mitchell
  • Brittany Fouts
  • Daniel P Cole
  • Kenneth Egerstrom
  • Lawrence Steinkraus
  • Susan Connor
  • Susan Dukes
  • William Butler

Organizations

  • 711th Human Performance Wing

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aeromedical Evacuation
  • Air Force
  • Air Force Research Laboratories
  • Altitude
  • Cardiovascular Physiological Phenomena
  • Data Science
  • Databases
  • Decompression Sickness
  • Evacuation
  • Health Services
  • Improvised Explosive Devices
  • Information Science
  • Military Medicine
  • Morbidity
  • Patient Care
  • Pilot Studies
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Regression Analysis.
  • Trauma or Military Medicine