Analgesics in the Pre-Hospital Setting: Implications on Hemorrhage Tolerance

Abstract

To date our findings demonstrate mean tolerance to a simulated hemorrhagic challenge is not different between when subjects received ketamine and placebo. However, variability in the responses were high in the male subjects, with some subjects showing rather profound reductions in tolerance with ketamine while others showed improvements in tolerance with ketamine. In contrast, responses in females were more homogeneous between ketamine and placebo trials. Future work is warranted to identify sex-related differences in the obtained findings.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2019
Accession Number
AD1095757

Entities

People

  • Craig G Crandall

Organizations

  • University of Texas Southwestern Medical Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Analgesia
  • Analgesics
  • Biomedical Research
  • Cardiovascular Physiological Phenomena
  • Casualties
  • Combat Casualty Care
  • Contracts
  • Department Of Defense
  • Health Services
  • Hemorrhage
  • Hemorrhagic Shock
  • Hospitals
  • Ketamine
  • Medical Personnel
  • Pain
  • Pain Management

Fields of Study

  • Medicine
  • Psychology

Readers

  • Organizational Psychology.
  • Trauma Surgery or Emergency Medicine.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.