Targeting BRCAness in Gastric Cancer

Abstract

In the past year, we have made substantial progress in the projects goals. We have set up a system (described below) to interrogate gastric cancer cells with ATR and PARP inhibitors. This screening platform is now up and running and we are prosecuting preliminary hits. Over the next year, we will validate hits generated here and further the interrogation of clinical samples.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2018
Accession Number
AD1095780

Entities

People

  • Yelena Janjigian

Organizations

  • Memorial Sloan Kettering Cancer Center

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • California
  • Cancer
  • Cell Count
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Chemotherapy
  • Department Of Defense
  • Diseases And Disorders
  • Genomic Instability
  • Inhibition
  • Inhibitors
  • Materials
  • Neoplasms
  • Oncology
  • Targeting

Fields of Study

  • Biology

Readers

  • Forest Ecology
  • Molecular Biology and Genetics
  • Radar Systems Engineering.