Ultrasound-Guided Percutaneous Peripheral Nerve Stimulation: A Non-Pharmacologic Alternative for the Treatment of Postoperative Pain

Abstract

The purpose of this two-stage, multicenter, randomized, double-masked, sham-controlled, human-subjects clinical trial is to evaluate the analgesic potential of ultrasound-guided percutaneous peripheral nerve stimulation (PNS) following painful ambulatory orthopedic surgery. The initial 2-year pilot study will estimate the treatment effects of percutaneous PNS on pain and opioid consumption to determine the appropriate sample size of the subsequent pragmatic clinical trial as well as to document the feasibility of and optimize the proposed protocol. The subsequent 4-year pragmatic trial will determine the effect of percutaneous PNS on postoperative analgesia and opioid requirements, as well as physical and emotional functioning, the development of chronic pain, and ongoing quality of life.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2019
Accession Number
AD1095831

Entities

People

  • Brian M Ilfeld

Tags

DTIC Thesaurus Topics

  • Analgesia
  • Biomedical Research
  • California
  • Clinical Trials
  • Contracts
  • Data Management
  • Medical Personnel
  • North Carolina
  • Pain
  • Patent Applications
  • Peripheral Nervous System
  • Personnel Management
  • Pilot Studies
  • Professional Development
  • Quality Of Life
  • Societies
  • Ultrasounds

Fields of Study

  • Medicine

Readers

  • Auditory Neuroscience/Auditory Physiology.
  • Clinical Trial Research.
  • Trauma or Military Medicine