Aptamer-Based Nano-Slit Platforms for Characterizing Human Performance Biomarkers

Abstract

In this manner, using DC-offset AC fields, differences in frequency dispersion for negative dielectrophoresis are balanced against electrophoresis in a nanoslit channel to enable the selective enrichment of prostate specific antigen (PSA) versus anti-mouse immunoglobulin antibodies that cause signal interferences to immunoassays. Through coupling enrichment to capture by receptors on graphene-modified surfaces, we demonstrate the elimination of false positives caused by anti-mouse immunoglobulin antibodies to the PSA immunoassay. Total of eight publications.

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Document Details

Document Type
Technical Report
Publication Date
Aug 14, 2019
Accession Number
AD1096607

Entities

People

  • Nathan S. Swami

Organizations

  • University of Virginia

Tags

Communities of Interest

  • Advanced Electronics
  • Human Systems

DTIC Thesaurus Topics

  • Abstracts
  • Air Force
  • Air Force Research Laboratories
  • Antibodies
  • Biomolecules
  • Chemical Synthesis
  • Chemistry
  • Conductivity
  • Department Of Defense
  • Detection
  • Detectors
  • Electric Fields
  • Frequency
  • Motor Skills
  • Nanoparticles
  • Proteins
  • Virginia

Fields of Study

  • Biology

Readers

  • Electronics Engineering
  • Immunology
  • Oncology and Biomarker-Based Cancer Detection.

Technology Areas

  • Microelectronics