Low-Cost, High-Throughput 3-D Pulmonary Imager Using Hyperpolarized Contrast Agents and Low-Field MRI

Abstract

This report covers the first year of the no-cost extension period. Overall, this is the fourth year of the project performance. During the indicated period of performance, we have focused our activities on all three specific aims. With regards to Aim #1 (129Xe polarizer development), we have been working on testing the 129Xe automated hyperpolarizer: to that goal, we have performed extensive tests of all key components of this device as we reported earlier and also focused on automation and integration completion. With regards to propane hyperpolarization, we have focused our efforts on additional tests and investigating the approaches to improve the quality of hyperpolarized propane gas. The remaining efforts will primarily focus on testing this device with the 0.35 T MRI scanner. With respect to the delivery and installation of 0.35 T MRI scanner, we have been engaged with the vendor to ensure that the delivered MRI scanner will be customized to our needs to meet the specifications for scan speed and resolution. As with previous years, we also note that we are submitting a duplicating report for two partnering PI awards of the same project: W81XWH-15-1-0271 and W81XWH-15-1-0272.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2019
Accession Number
AD1097342

Entities

People

  • Boyd M Goodson

Organizations

  • Southern Illinois University Carbondale

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Chemical Analysis
  • Chemical Kinetics
  • Chemical Reactions
  • Chemical Synthesis
  • Chemistry
  • Computational Science
  • Detectors
  • Health Services
  • Isotopes
  • Lasers
  • Lung Diseases
  • Magnetic Resonance
  • Medical Personnel
  • Nuclear Magnetic Resonance
  • Organic Chemistry
  • Radio Frequency Pulses
  • Three Dimensional

Fields of Study

  • Medicine

Readers

  • Medical Imaging.
  • Software Engineering