Non-invasive Urine Markers of Interstitial Cystitis

Abstract

Interstitial cystitis/painful bladder syndrome (IC) is a debilitating condition that presents with a confusing array of symptoms, including bladder pain, urinary urgency, frequency, nocturia, and small voided volumes in the absence of other identifiable symptoms. Currently, the diagnosis of IC is largely dependent on subjective parameters, leading to extreme difficulties in accurately phenotyping patients. There is no gold standard for IC diagnosis. In general, it takes approximately 4-5 years from the first office visit to obtain a definitive diagnosis of IC. Thus, differentiating IC from other conditions is still a diagnostic challenge, and objective diagnostic markers are urgently needed to improve prospects for clinical care. In this study, we will assess whether these promising biomarkers can segregate IC patients from control subjects, and whether they are potentially involved in bladder pain.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2019
Accession Number
AD1097679

Entities

People

  • Jayoung Kim

Organizations

  • Cedars-Sinai Medical Center

Tags

DTIC Thesaurus Topics

  • Amines
  • Cell Physiological Processes
  • Cells
  • Chemical Compounds
  • Chemical Synthesis
  • Chemistry
  • Colon Cancer
  • Computational Biology
  • Computational Science
  • Databases
  • Genetics
  • Health Services
  • Liquid Chromatography
  • Mass Spectrometry
  • Medical Personnel
  • Metabolic Diseases
  • Metabolism
  • Organic Chemistry
  • Pain
  • Surveys
  • Virtual Reality

Fields of Study

  • Medicine

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