Parameters for Estimation of Casualties from Exposure to Specified Biological Agents: Brucellosis, Glanders, Q Fever, SEB and Tularemia

Abstract

The U.S. Army Office of The Surgeon General (OTSG) tasked IDA with developing human response models for five prospective non-contagious biological warfare agents, using the methodology contained in Allied Medical Publication 8(C): NATO Planning Guide for the Estimation of CBRN Casualties (AMedP-8(C)). The five agents considered in this document are brucellosis, glanders, Q fever, staphylococcal enterotoxin B (SEB), and tularemia. For each agent, the authors propose parameters and values for models of infectivity, lethality, incubation period, and duration of illness. The authors also describe profiles of illness over time for each agent based on symptoms and their associated severity, using the scale developed in AMedP-8(C). The work described in this document is based on an extensive review of available literature and subsequent evaluation of existing models, experimental data sets--both human and animal--and clinical case studies.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 2010
Accession Number
AD1099177

Entities

People

  • Carl A. Curling
  • Julia K. Burr
  • Kristen A. Bishop
  • Lucas A. Laviolet
  • Margaret C. Hebner
  • Preston J. Lee

Organizations

  • Institute for Defense Analyses

Tags

DTIC Thesaurus Topics

  • Chemical Synthesis
  • Chemistry
  • Geography
  • Health Services
  • Medical Personnel

Fields of Study

  • Medicine

Readers

  • Computational Modeling and Simulation
  • Microbial Pathology
  • Trauma or Military Medicine