Breast Cancer Prognostic Factors in the Digital Era: Comparison of Nottingham Grade Using Whole Slide Images and Glass Slides

Abstract

Background: To assess reproducibility and accuracy of overall Nottingham grade and component scores using digital whole slide images (WSIs) compared to glass slides. Conclusions: Pathologists' intraobserver agreement (reproducibility) is similar for Nottingham grade using glass slides or WSI. However, slightly lower agreement between pathologists suggests that verification of grade using digital WSI may be more challenging.

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Document Details

Document Type
Technical Report
Publication Date
Apr 03, 2019
Accession Number
AD1100232

Entities

People

  • Donald L. Weaver
  • Ezgi Mercan
  • Joann Elmore
  • Kimberly H. Allison
  • Linda G. Shapiro
  • Mara H. Rendi
  • Paul D. Frederick
  • Tad T Brunyé
  • Tara M. Davidson
  • Tracy Onega

Organizations

  • United States Army Soldier Systems Center

Tags

DTIC Thesaurus Topics

  • Accuracy
  • Breast Cancer
  • California
  • Carcinoma
  • Computer Science
  • Data Analysis
  • Digital Images
  • Homogeneity
  • Medical Personnel
  • Neoplasms
  • Public Health
  • Reproducibility
  • Schools
  • Statistical Analysis
  • Training
  • United States
  • Universities

Fields of Study

  • Chemistry
  • Medicine

Readers

  • Oncology and Biomarker-Based Cancer Detection.