Development and Testing of New Noninvasive Monitoring Tools for Prolonged Field Care Goal-Directed Therapy

Abstract

Management of the polytrauma patient with or without TBI in the prolonged field care (PFC) setting especially when prolonged damage control resuscitation (pDCR) is required represents an extraordinary challenge. While there is a desire to develop new therapeutic agents to improve survival and mitigate tissue injury and organ failure, we have not yet developed tools which assist in helping providers maximize use of supportive treatments such blood transfusion, volume expansion, vasopressor use, etc. in a precision manner for goal directed therapy (GDT). The use of goal GDT has been demonstrated to be life saving for both surgical and medical populations with severe hemodynamic compromise but is difficult to implement with current invasive and noninvasive tools because of their lack of precision or form factor and expense. This proposal will scale testing of two novel noninvasive measures that could allow for real-time use of GDT in the PFC/pDCR setting.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2020
Accession Number
AD1103062

Entities

People

  • Kevin Ward
  • Mohamad H Tiba

Organizations

  • University of Michigan

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Arteries
  • Blood
  • Blood Transfusions
  • Cardiovascular Physiological Phenomena
  • Data Analysis
  • Data Science
  • Health Services
  • Measurement
  • Medical Personnel
  • Oxygenation
  • Patient Care
  • Public Health
  • Raman Spectroscopy
  • Standards
  • Therapy
  • Veins

Fields of Study

  • Medicine

Readers

  • Military Logistics and Supply Chain Management
  • Systems Analysis and Design
  • Trauma or Military Medicine