Perovskite Nickelates as Bio-Electronic Interfaces

Abstract

Functional interfaces between electronics and biological matter are essential to diverse fields including health sciences and bio-engineering. Here, we report the discovery of spontaneous(no external energy input) hydrogen transfer from biological glucose reactions into SmNiO3,an archetypal perovskite quantum material. The enzymatic oxidation of glucose is monitored down to tilde5 10(exp-16) M concentration via hydrogen transfer to the nickelate lattice. The hydrogen atoms donate electrons to the Ni d orbital and induce electron localization through strong electron correlations. By enzyme specific modification, spontaneous transfer of hydrogen from the neurotransmitter dopamine can be monitored in physiological media. We then directly interface an acute mouse brain slice onto the nickelate devices and demonstrate measurement of neurotransmitter release upon electrical stimulation of the striatum region. These results open up avenues for use of emergent physics present in quantum materials in trace detection and conveyance of bio-matter, bio-chemical sciences, and brain-machine interfaces.

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Document Details

Document Type
Technical Report
Publication Date
Apr 10, 2019
Accession Number
AD1103503

Entities

People

  • Alexander A Chubykin
  • Badri Narayanan
  • Fan Zuo
  • Feiran Li
  • Ganesh Kamath
  • Gobinda Saha
  • Hai-Tian Zhang
  • Henry Chan
  • Hua Zhou
  • Indranil Chakraborty
  • Jong H. Choi
  • Kaushik Roy
  • Koushik Ramadoss
  • Qiuyu Wu
  • Shriram Ramanathan
  • Subramanian K. Sankaranarayanan
  • Zhan Zhang

Organizations

  • Purdue University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biological Sciences
  • Charge Carriers
  • Chemical Reactions
  • Chemistry
  • Crystal Lattices
  • Diseases And Disorders
  • Dynamics
  • Engineering
  • Hydrogen
  • Materials
  • Materials Engineering
  • Molecular Dynamics
  • Parkinson'S Disease
  • Reaction Mechanisms
  • Resistance
  • Simulations
  • X Rays

Fields of Study

  • Physics

Readers

  • Analytical Chemistry
  • Neuroscience
  • Quantum Dot Semiconductor Device Photonics and Graphene Optoelectronic Materials and THz Physics.

Technology Areas

  • Microelectronics
  • Microelectronics - Graphene
  • Quantum Computing
  • Space