Killing it: Can a Biofilm-Disrupting, Antimicrobial Wound Cleanser Improve Wound Healing?

Abstract

Antibiotic-resistant infections are becoming increasingly prevalent and are a major concern for both civilian and military health systems. Combat wounds, in particular, are prone to infection and may develop hard-to-treat biofilms due to delayed treatment. A product that disrupts microbial biofilm and kills the biofilm-protected micro-organisms, while not damaging human tissue, may lead to infection mitigation so chronic wounds can progress to healing. Furthermore, with biofilm disruption, microbes lose their protection such that systemic antibiotics as well as topical antimicrobials can be effective. Objectives: We sought to compare the effectiveness of BIAKS Antimicrobial Skin and Wound cleanser to Vashe Wound cleanser in the ability to decrease biofilm formation in chronic wounds as well as the ability to decrease healing time of chronic wounds. We conducted this clinical evaluation as retrospective chart review.

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Document Details

Document Type
Technical Report
Publication Date
Jul 21, 2020
Accession Number
AD1104254

Entities

People

  • Valerie G. Sams

Organizations

  • 59th Medical Wing

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacterial Infections And Mycoses
  • Chemotherapy
  • Combat Casualty Care
  • Combat Injuries
  • Department Of Defense
  • Dermatologic Agents
  • Diseases And Disorders
  • Drug Therapy
  • Health
  • Hygiene
  • Infection
  • Luminescence
  • Military Medicine
  • Patient Care
  • Test And Evaluation
  • Therapy
  • Wound Healing
  • Wound Infections
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Microbial Pathology
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology