Successful Use of COVID-19 Convalescent Plasma in a Patient Recently Treated for Follicular Lymphoma

Abstract

Coronavirus disease 2019 (COVID-19) has swept the globe and poses unique treatment challenges for immunocompromised patients with hematologic malignancies. Here, we present the case of a 54-year-old man with follicular lymphoma, recently completing treatment with maintenance rituximab, who endured a protracted course of COVID-19. The patients case was complicated by evolving hypoxic respiratory failure, marked lymphopenia, and hypogammaglobulinemia, which ultimately led to treatment with COVID-19 convalescent plasma, resulting in clinical improvement. Presently, there is no definitive data on the efficacy ofCOVID-19 convalescent plasma in patients withCOVID-19; however, many trials are ongoing. We propose that this may be an effective treatment inpatients treated for lymphoma with subsequent lymphopenia and hypogammaglobulinemia.

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Document Details

Document Type
Technical Report
Publication Date
Jun 19, 2020
Accession Number
AD1105950

Entities

People

  • Adrian Bersabe
  • Andrew P Cap
  • Rina Eden
  • Zachary Wright

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Cancer
  • Chemical Reactions
  • Covid-19
  • Department Of Defense
  • Disease Outbreaks
  • Diseases And Disorders
  • Electronic Mail
  • Emergency Treatment
  • Health Care
  • Health Services
  • Immunoproteins
  • Stem Cells
  • Transplants
  • Viruses
  • X Rays

Fields of Study

  • Biology
  • Medicine

Readers

  • Gulf War Illness and Chronic Multisymptom Illness in Veterans.
  • Oncology
  • Toxicology/Environmental Toxicology