Electroceutical Technology Against Bacterial Drug Resistance

Abstract

The objective of this work is to develop EDT(1o) and EDT(hi) wound dressings against bacteria and fungal biofilm infections as MTEC Technology for prototype acceleration. Resilience, DoD). Two sp aims have been proposed: Aim 1. Demonstrate the ability of optimized electroceutical EDT dressings to eliminate mixed species, multi-drug resistant infection in an invitro assay and porcine burn infection model. Aim 2.Conduct a pilot study to test whether infected wound closure in a pair-matched setting is improved using optimized EDT treatment compared to standard of care (SoC).

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Document Details

Document Type
Technical Report
Publication Date
Jun 15, 2020
Accession Number
AD1106052

Entities

People

  • Chandan K Sen
  • Dolly Khona
  • Gayle M. Gordillo
  • Nandini Ghosh
  • Sashwati Roy
  • Savita Khanna
  • Vinoj Gopalakrishan

Organizations

  • Indiana University School of Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bacteria
  • Bandages
  • Contracts
  • Covid-19
  • Department Of Defense
  • Drug Resistance
  • Education
  • Electron Microscopes
  • Electron Microscopy
  • Electronic Mail
  • Governments
  • Infection
  • Medical Personnel
  • Microscopy
  • Pilot Studies
  • Resistance
  • Wound Infections

Readers

  • Parasitology and Pharmacology of Malaria.
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology