A Prospective, Randomized Investigation of "Plasma First Resuscitation" for Traumatic Hemorrhage and Attenuation of the Acute Coagulopathy of Trauma

Abstract

The COMBAT (Control of Major Bleeding After Trauma) study is a randomized clinical trial evaluating the early administration of plasma, compared to the standard crystalloid. Over the past year, we have worked on refining our procedures and workflows, collecting accurate and timely data, ensuring regulatory compliance, and communicating with all study team personnel at Denver Health and the University of Colorado Anschutz Medical Campus. We have enrolled a total of 98 patients to-date and 41 patients this reporting year. We have collected over 4,500 samples this year, in addition to submitting our annual continuing review, publishing and presenting several papers.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2020
Accession Number
AD1110049

Entities

People

  • Arsen Ghasabyan
  • Ernest Moore
  • Jacob Feiler

Organizations

  • University of Colorado Boulder

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Acquisition
  • Biomedical Research
  • Blood
  • Blood Transfusions
  • Cardiovascular Physiological Phenomena
  • Clinical Trials
  • Colorado
  • Communities
  • Contracts
  • Data Analysis
  • Department Of Defense
  • Electronic Mail
  • Health Care
  • Health Services
  • Hemorrhage
  • Institutional Review Board
  • Liquid Chromatography
  • Mass Spectrometry
  • Medical Personnel
  • Procurement
  • Universities

Fields of Study

  • Medicine

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Technical Research and Report Writing.
  • Trauma or Military Medicine