Quantitative MRI of the Post-Injury Instrumental Spinal Cord

Abstract

This study seeks to improve monitoring of spinal cord health after injury using magnetic resonance imaging (MRI) in the presence of commonly encountered implanted hardware. In an effort to improve monitoring, this study will enhance technological imaging capabilities targeting diagnostic-quality MRI near implanted metal hardware in the spinal cord and demonstrate the medical utility of metal-artifact reduction techniques in patients with spinal cord injury and degenerative cord damage. A multidisciplinary team of surgeons, spinal cord scientists, and physicists will then deploy these methods to injured, degenerated, and control cohorts. We hypothesize that morphological and diffusion-weighted MRI will provide useful quantitative imaging biomarkers for assessment of treatment effectiveness and recovery progress.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2020
Accession Number
AD1110678

Entities

People

  • Kevin M. Koch

Organizations

  • Medical College of Wisconsin

Tags

Communities of Interest

  • Air Platforms
  • Human Systems

DTIC Thesaurus Topics

  • Acquisition
  • Biomedical Research
  • Brain Injuries
  • Clinical Trials
  • Data Analysis
  • Data Curation
  • Department Of Defense
  • Detection
  • Genetic Markers
  • Health
  • Image Processing
  • Information Science
  • Medical Personnel
  • Natural History
  • Physicians
  • Spinal Cord
  • Spinal Injuries

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical Imaging.
  • Neurotrauma and Rehabilitation Medicine.