7.4 Reactive Chemical Systems: Effects of Nanoscale Chemical Heterogeneity on Hydrophobic Interactions and Molecular Assembly at Surfaces

Abstract

Overview: This ARO grant enabled our collaborative team to undertake fundamental studies of hydrophobically driven association processes. Because hydrophobic interactions underlie many phenomena of biological and technological importance, the surprising insights generated by this research suggest a need for broad reconsideration of the role of hydrophobic forces in folding, recognition and assembly phenomena that occur in water. ARO support enabled us to apply a powerful and nontraditional combination of molecular design, chemical synthesis and physical analysis to elucidate the modulation of hydrophobic forces by proximal polar functionality. This multidisciplinary research provided an outstanding training environment for the participating students.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Feb 29, 2020
Accession Number
AD1111080

Entities

People

  • Samuel H. Gellman

Organizations

  • University of Wisconsin–Madison

Tags

Communities of Interest

  • Energy and Power Technologies

DTIC Thesaurus Topics

  • Adhesion
  • Alcohols
  • Aqueous Solutions
  • Chemical Synthesis
  • Chemistry
  • Contrast
  • Free Energy
  • Hydrophobic Properties
  • Molecules
  • Raman Spectra
  • Recognition
  • Self Assembly
  • Sequences
  • Simulations
  • Spectra
  • Spine
  • Students

Fields of Study

  • Chemistry

Readers

  • Molecular and Cellular Biochemistry
  • Research Science/Academic Research
  • Theoretical Analysis.