Desmoid-Type Fibromatosis of the Lower Extremity: A Unique Case of Complete Lesion Resolution Following Core Needle Biopsy

Abstract

Desmoid-type fibromatosis (DF) is a rare neoplasm characterized by fibroblastic and myofibroblastic proliferation. While characterized as a benign lesion that does not metastasize, desmoid-type fibromatosis exhibits a wide range of behavior from aggressive local tissue invasion and post-surgical recurrence to spontaneous regression. Tumor regression can occur following systemic medical therapy or rarely may occur in the absence of therapy. We present a case of a 50-year-old female with a left thigh vastus medialis intramuscular mass which underwent imaging work-up and subsequent core needle ultrasound-guided biopsy showing results of desmoid-type fibromatosis. Following biopsy, the tumor showed prompt, complete regression with complete MRI resolution 2 months following biopsy.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2020
Accession Number
AD1111308

Entities

People

  • Dawood Tafti
  • Erica Kao
  • Joseph F. Alderete
  • Nathan D. Cecava

Organizations

  • 59th Medical Wing

Tags

DTIC Thesaurus Topics

  • Abdomen
  • Cancer
  • Carcinoma
  • Cell Count
  • Cell Physiological Processes
  • Cells
  • Diseases And Disorders
  • Drug Therapy
  • Medical Personnel
  • Neoplasms
  • Oncology
  • Physicians
  • Radiation Oncology
  • Sarcoma
  • Skeletal Muscle
  • Soft Tissues
  • Therapy
  • Tissues
  • Ultrasounds
  • X-Ray Computed Tomography

Fields of Study

  • Medicine

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Trauma Surgery or Emergency Medicine.