Transform Off-the-Shelf Synthetic Grafts to Autologous Conduits for Coronary Artery Bypass Grafting

Abstract

INTRODUCTION: Coronary arterial disease is the leading cause of death in the United States in both women and men. Arterial disease of theheart alone costs well over $2.5B for the VA system alone. To meet this challenge, we design vascular grafts made of special rubbers that aredesigned and patented specifically for vascular grafting. Unlike current grafts on the market or in clinical trials, the patients own body willchange these grafts over time to their own vessels. The two aims of this project are: 1. Finalize graft fabrication methodology and select thebest design using a rat carotid artery model. And 2. Evaluate the performance of the selected grafts in a pig coronary artery bypass graftingmodel.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2020
Accession Number
AD1111957

Entities

People

  • Yadong Wang

Organizations

  • Cornell University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acetonitrile
  • Arteries
  • Biomedical Research
  • Cells
  • Chemistry
  • Fabrication
  • Formic Acid
  • Governments
  • Health Services
  • Local Governments
  • Maryland
  • Materials
  • Medical Personnel
  • Professional Development
  • Proteins
  • Students
  • United States

Fields of Study

  • Medicine

Readers

  • Data Mining and Knowledge Discovery.
  • Medical or Health Care Field.
  • Trauma Surgery or Emergency Medicine.