A Low-Cost, Composite Collagen-PDMS Material for Extended Fluid Retention in the Skin-Interfaced Microfluidic Devices (Postprint)

Abstract

The advancement of soft, wearable microfluidic devices relies on the microfabrication of polydimethylsiloxane (PDMS) using soft lithography techniques. However, thin 3D microstructures made of PDMS limit long-term storage of aqueous samples and reduce the accuracy of onboard sensing modalities within the platform because of the material's high permeation of water vapor. We studied a composite material of collagen microparticles and PDMS that greatly reduces water evaporation while maintaining the properties of a soft elastomer required for skin-interfaced microfluidics. The collagen-PDMS material is biocompatible, affordable, and non-toxic. We reduced permeability by 80.2 by building a film containing 30 wt collagen microparticles. Mechanical properties, such as elastic modulus and bonding efficacy, can vary as a function of particle concentration in the films. The skin-interfaced collagen-PDMS microfluidic devices increase sweat retention by 45 through 9 h compared with pure PDMS. This material can greatly improve the long-term sample storage of epidermal devices.

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Document Details

Document Type
Technical Report
Publication Date
Aug 11, 2020
Accession Number
AD1112195

Entities

People

  • Ahyeon Koh
  • Benjamin Heo
  • Ji H. Yang
  • Michael Fiola

Organizations

  • Binghamton University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Accuracy
  • Air Force
  • Air Force Research Laboratories
  • Composite Materials
  • Elastomers
  • Films
  • Fluids
  • Governments
  • Materials
  • Mechanical Properties
  • Microparticles
  • Modulus Of Elasticity
  • New York
  • Particles
  • Permeability
  • Soft Lithography
  • Water Vapor

Readers

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