Layered and Integrated Medical Intervention Technologies (LIMIT) Concept Phase 1: Science-Informed Rules for Layering ofVaccines and Antibody Medical Countermeasures to Protect Against Biological Threat Agents
Abstract
The mission of the Warfighter Integration Division (CBW) of the Defense Threat Reduction Agency (DTRA) Chemical and Biological Department is to foster strategic partnerships with chemical and biological science and technology (S and T) communities to deliver the best innovations to Department of Defense (DoD) operational capability and enhance global collaboration in biodefense and global health. This is accomplished through active engagement and S and T portfolio integration with the warfighter via experimentation and concept development, tabletop exercises, war gaming, advanced technology demonstrations, and Warfighter utility assessments. The DoD Chemical Biological Defense Program Planning Guidance for Fiscal Year 2019-2029included the objective to field integrated layered chemical, biological, radiological, and nuclear(CBRN) defense capabilities that advance the DoD ability to operate and succeed in a CBRN threat environment. CBW is working toward addressing this guidance through pursuit of a concept to develop a science-informed methodology for layering of medical countermeasures(MCM).This concept paper presents the science-informed justification and outlines a methodology to define layering rules for vaccines and antibody MCM and considers how layering can widen the protection window against biological threats. This initial concept build was scoped to and considers preparedness specifically through the administration of MCM during operational planning and predeployment phases to optimize Warfighter protection against biological threat agents during deployment.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 30, 2020
- Accession Number
- AD1114457
Entities
People
- Kimberly A. Hofmeyer
- Tiffany Tsang
Organizations
- MITRE Corporation