Using Early Time-Restricted Feeding and Timed Light Therapy to Improve Glycemic Control in Adults with Type 2 Diabetes
Abstract
In this clinical trial, we will test whether two circadian-based therapies--a form of meal timing called early time-restricted feeding (eTRF) and timed light therapy--can improve blood sugar control in adults with type 2 diabetes. Approximately 344 adults with type 2 diabetes will be randomized to the following 2 x 2 study design: (1) control group, (2) eTRF, (3) timed light therapy, and (4) eTRF and timed light therapy. Participants will follow their assigned lifestyle intervention for 16 weeks and be followed for a total of one year. In addition, we will determine whether the two circadian therapies can improve circadian rhythms, sleep quality, weight loss, cardiovascular health, quality of life, and psychological health. We will also determine which patients benefit the most from these therapies. During the first year of this award, we set-up the clinical trial. We hired and trained the core research staff; refined the protocol; secured initial IRB and HRPO approval; built the study database; designed the counseling sessions and handouts; completed all contracts and data agreements; created all SOPs; and acquired and (mostly) set-up the inpatient testing facilities. Study recruitment and in-person activities were put on hold in mid-March 2020 due to the COVID-19 pandemic and will re-open in the first quarter of Year 2.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2020
- Accession Number
- AD1115266
Entities
People
- Courtney M. Peterson
- Kimberly Armstead
- Rachel Benz
Organizations
- University of Alabama