Racial Disparities in Active Surveillance Adherence and Quality of Life in a Population-Based Prospective Cohort of Men with Low-Risk Prostate Cancer
Abstract
The proposed project extends follow-up of a population-based cohort study of over 1800 (~21% AA) patients diagnosed with low-risk LPC from 2014 to 2017 prospectively recruited through two NCI-sponsored SEER registries. All cases who initially chose AS or watchful waiting (WW), and a subset of cases who received surgery or radiation at baseline were selected for a follow-up survey at 18 months after baseline. Due to the long natural history of low-risk LPC, a follow-up beyond 18 months is necessary to adequately assess the outcomes. Aim 1: Identify racial differences in mens adherence to AS protocol, switch rates and time to curative treatment over the course of 5 years from diagnosis Aim 2: Compare quality of life (QOL) measures between the AS group and curative treatment group over the course of 5 years Aim 3: Evaluate whether reasons for switching from AS to curative treatment differ by race So far, we have obtained IRB approval from both Wayne State University and Emory University and subsequently obtained HRPO approval for the study on schedule. We have started to administer the 5-year follow-up survey in Feb. 1, 2020. As of now, we have received total of 280 completed surveys, which is 32% of expected sample size (n=880). The recruitment is ongoing from both study sites.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2020
- Accession Number
- AD1115274
Entities
People
- Jinping Xu
Organizations
- Wayne State University