Novel Therapeutics for Fibrolamellar Carcinoma

Abstract

In Project 3, we have made substantial progress despite a slow-down of research activities due to the ongoing COVID-19 pandemic. We have found that immune cells in FLC are biased towards being in the stromal bands or peritumoral interface. We have found that PD-1 and IL-10 blockade each have some effects against FLC slice cultures in vitro. We are presently completing a manuscript detailing our findings from the first year of the project.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2020
Accession Number
AD1117697

Entities

People

  • Venu G Pillarisetty

Organizations

  • University of Washington

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Acquisition
  • Biomedical Research
  • Buildings And Structures
  • Cells
  • Continents
  • Contracts
  • Covid-19
  • Data Analysis
  • Department Of Defense
  • Electronic Mail
  • Geographic Regions
  • Immunomodulation
  • Information Operations
  • Lymphocytes
  • Maryland
  • North America
  • Procurement
  • Research Facilities
  • Rna Sequence Analysis
  • Therapy
  • United States
  • Universities

Fields of Study

  • Medicine

Readers

  • Molecular Biology and Genetics
  • Molecular and Cellular Biology
  • Technical Research and Report Writing.