Neostigmine and Glycopyrrolate by Iontophoresis to Induce Bowel Evacuation

Abstract

The proposed research project to determine the correct dose of these medications and the correct ratio of them is anticipated to take two years. Then, during the third year of this grant, the investigators will study the possibility of using wireless iontophoresis devices to induce bowel evacuation. A manufacturer of wireless iontophoresis systems has been in contact with the investigators and shown interest in modifying the current device on the market to one that will be easier to use for someone with SCI, and the device would be designed to be more functionally appropriate to administer these drugs to elicit bowel evacuation. The final step to commercialization would be to obtain approval from the Food and Drug Administration (FDA) to market the wireless iontophoresis device with both medications in a patch system with the indication for constipation.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2020
Accession Number
AD1119068

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  • Mark A. Korsten

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