Design and Computer Simulations of 2D MeX2 (Me=transition metal) Nanopores for DNA and Protein Detection and Analysis
Abstract
Three main results: (1) an analysis based on the current threshold to extract and characterize meaningful sensing events from ionic current time series computed from molecular dynamics. (2) A mechanism of translocation was established, for which side chains of each amino acid are oriented parallel to the electric field when they are translocating through the pore and perpendicular otherwise. (3) A new procedure based on the permutation entropy algorithm was detailed to identify protein sequence motifs related to ionic current drop speed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 17, 2020
- Accession Number
- AD1119752
Entities
People
- Patrick Senet