Why Does Acute Postwhiplash Injury Pain Transform into Chronic Pain? Multimodal Assessment of Risk Factors and Predictors of Pain Chronification
Abstract
This project aim to find why some acute mTBI patients turn into chronic pain patients, and other do not. We recruit patients immediately after the accident, and get them through clinical, psychophysical and psychological assessment, brain MRI, EEG, and genetic tests. We then follow up on the pain levels along one year. All clinical work is done in Israel, analysis is done in cooperation with leading teams in the US, Canada and Australia. Up to date, we recruited 458 patients, 244 of them completed the first visit performed within 72 hours after the accident, 63 patients gave blood samples for RNA sequencing in genetics data collection. 187 participants answered the 3 months follow up questions, 183 answered the 6 months, and 163 answered the 12 months follow up questions. 89 participated in the 6 months visit and 66 participated in the 12 months visit, of which 36 participants were tested in both sessions. The rest failed to continue with the protocol despite their initial consent and are dropouts.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 30, 2020
- Accession Number
- AD1121766
Entities
People
- David Yarnitsky