Clinical Assessment of Vertebral Bone Quality Using Direct Biomechanical and Textural Analysis via Digital Tomosynthesis

Abstract

Osteoporosis (OP) is one of the most common diseases affecting aging individuals and vertebral fractures are the most common type of fracture, complicating osteoporosis. Current techniques for assessing bone strength and osteoporotic fracture risk may be inaccurate and ultimately measure surrogates for biomechanical properties. The proposed research idea is based on the digital volume correlation (DVC) technique, which allows for measurement of displacements inside a porous object such as a vertebra, in response to an applied load. In using DVC combined with digital tomosynthesis (DTS), we can measure the in vivo, patient-specific biomechanical response of vertebrae to load. The overall objective of the proposed research is to clinically validate new DTS-based textural and DVC methods for identification of patients at risk of vertebral fractures in clinically significant cohorts.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2020
Accession Number
AD1122473

Entities

People

  • D. Sudhaker Rao
  • Yenar N. Yeni

Organizations

  • Henry Ford Health

Tags

DTIC Thesaurus Topics

  • Acquisition
  • Biomedical Research
  • Bone Diseases
  • Bone Fractures
  • Covid-19
  • Data Analysis
  • Data Processing
  • Diabetes
  • Diseases And Disorders
  • Geometry
  • Health
  • Health Services
  • Identification
  • Image Processing
  • Imaging Techniques
  • Institutional Review Board
  • Medical Personnel
  • Orthopedics
  • Pain
  • Spinal Column
  • Spine
  • Standards
  • Statistical Analysis
  • Tomosynthesis
  • Type 2 Diabetes
  • X Rays

Fields of Study

  • Medicine

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