Enzymes, Directed Evolution

Abstract

Staunch Darwinists attribute all the complexity of living things to an algorithm of mutation and natural selection. The exquisite products of this evolution algorithm are apparent at all levels, from the amazing diversity of life all the way down to individual protein molecules. Scientists and engineers who wish to redesign these same molecules are not implementing their own versions of the algorithm. Directed evolution allows us to explore enzyme functions never required in the natural environment and for which the molecular basis is poorly understood.

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Document Details

Document Type
Technical Report
Publication Date
Apr 13, 1999
Accession Number
AD1125512

Entities

People

  • Frances Arnold
  • Patrick L. Wintrode

Organizations

  • University of Minnesota

Tags

DTIC Thesaurus Topics

  • Algorithms
  • Engineers
  • Environment
  • Molecules
  • Mutations
  • Personal Information Managers
  • Scientists

Readers

  • Military History of the United States in the 20th Century.
  • Molecular and Cellular Biochemistry
  • Systems Analysis and Design