Anticoagulant Vascular Shunts for Temporary Arterial Bypass

Abstract

Temporary vascular shunts are essential for repairing severely damaged arterial blood vessels following extreme trauma in the combat casualty care setting. Unfortunately, recent experience in Iraq showed clotting and occlusion of existing shunts within hours. In the current research we coated shunts with a novel non-adhesive surface coating technology developed at the Wyss Institute, and tested both short and long-term patency in large animal (pig) models of thrombosis.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2020
Accession Number
AD1125523

Entities

People

  • Donald E. Ingber
  • Michael Super

Organizations

  • Harvard University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Anticoagulants
  • Arteries
  • Biomedical Research
  • Blood
  • Blood Coagulation
  • Blood Coagulation Factors
  • Blood Flow
  • Blood Vessels
  • Cardiovascular Physiological Processes
  • Casualties
  • Cells
  • Combat Casualty Care
  • Combat Injuries
  • Electron Microscopy
  • Electronic Mail
  • Epithelial Cells
  • Flow Rate
  • Health Services
  • Hydrophobic Properties
  • Materials
  • Professional Development
  • Therapy

Fields of Study

  • Medicine

Readers

  • Trauma Surgery or Emergency Medicine.