High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury

Abstract

The purpose of this research is to use high-definition transcranial direct current stimulation (HD-tDCS) to treat neurosensory postconcussive symptoms (PCS) associated with mild traumatic brain injury (mTBI) in US Veterans and Warfighters. A randomized sham-controlled clinical trial will be performed. We will recruit 120 participants ages 18-59 for the study: 80 participants with mTBI to undergo the intervention, and 40 non-TBI healthy subjects to act as an imaging-only control group. The intervention is 10 days of anodal HD-tDCS to the left dorsolateral prefrontal cortex, paired with vision therapy and cognitive training. Magnetic source imaging (MSI), neuropsychological assessment, and neurosensory evaluation, are obtained before and after the intervention, to assess changes in brain function, postconcussive symptom burden, and quality of life. During this reporting period, preliminary data has been generated demontrating improvements in neurosensory function, cognitive control, and brain activation patterns with the intervention.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2020
Accession Number
AD1126832

Entities

People

  • Davin Quinn

Organizations

  • University of New Mexico

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Brain Injuries
  • Clinical Trials
  • Covid-19
  • Data Analysis
  • Department Of Defense
  • Direct Current
  • Diseases And Disorders
  • Electric Current
  • Employment
  • Eye Movements
  • Health
  • Health Care
  • Health Services
  • Institutional Review Board
  • Medical Personnel
  • New Mexico
  • Personnel Management
  • Public Health
  • Test And Evaluation
  • Therapy
  • Training
  • Traumatic Stress Disorder

Fields of Study

  • Medicine
  • Psychology

Readers

  • Neuroscience
  • Neurotrauma and Rehabilitation Medicine.
  • Traumatic Brain Injury (TBI) and Cognitive Aging in the Guam and Border Populations Affected by Alzheimer's Disease and Tau-Associated Dementias.