Diagnosis and Treatment of TBI and Polytrauma during Ground and High-Altitude Evacuation using Liquid Biopsy and Extracorporeal Life Support

Abstract

TBI alone and in combination with polytrauma and lung injury caused up to 83 percent of nonsurvivable combat-related deaths. There is no accurate diagnosis method or viable therapeutic intervention for these casualties primarily due to the severity of injury, which can be unrecognized early on. Our proposal will address these unmet needs via utilization of a model of TBI with targeted descriptors of injury severity derived from bedside cell free DNA (cfDNA) testing, and then via addition of polytrauma and lung injury with subsequent testing of therapeutic intervention via extracorporeal life support (ECLS).

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2021
Accession Number
AD1127520

Entities

People

  • Andriy I. Batchinsky

Organizations

  • Geneva Foundation

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Altitude
  • Biological Markers
  • Biomedical Research
  • Blood
  • Blood Proteins
  • Brain
  • Brain Injuries
  • Cardiovascular Physiological Phenomena
  • Covid-19
  • Data Mining
  • Digital Data
  • Evacuation
  • High Altitude
  • Intervention
  • Lung Diseases
  • Materials
  • Medical Personnel
  • Military Medicine
  • Standards
  • Therapy
  • Thoracic Injuries
  • Tissues
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Oncology
  • Trauma or Military Medicine