Catecholamine Augmented RyR1 Ca2+ Release In Malignant Hyperthermia Sensitive Human B-Lymphocytes

Abstract

The purpose of this paper is to examine the possibility that activation of the stress response in Malignant Hyperthermia susceptible (MHS) individuals results in an adrenergic augmentation of intracellular Ca2 release in a way that is different from patients that are not MHS and that this augmentation is involved in the triggering of Malignant Hyperthermia.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2012
Accession Number
AD1127726

Entities

People

  • Susan M. Browder Perry

Tags

DTIC Thesaurus Topics

  • Amines
  • Analgesia
  • Anesthesia
  • Anesthesia And Analgesia
  • Anesthesiology
  • B Lymphocytes
  • Blood
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Department Of Defense
  • Diseases And Disorders
  • Genetics
  • Information Science
  • Liquid Chromatography
  • Lymphocytes
  • Medical Personnel
  • Muscle Cells
  • Muscular Diseases
  • Nervous System
  • Organic Chemistry
  • Regression Analysis
  • Skeletal Muscle
  • Statistical Analysis
  • Test Methods

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Oncology (Cancer Research).